Table 5. Pooled analysis of rs2010963: G allele of G/C SNP designated high risk.
Study | No. Probands | OR | 95% CI Low | 95% CI High |
Stalmans | 58 | 1.30 | 0.80 | 2.00 |
Lambrechts TOF | 148 | 1.43 | 1.00 | 2.02 |
Lambrechts TGA | 40 | 1.23 | 0.59 | 2.56 |
Vannay | 102 | 0.37 | 0.24 | 0.56 |
Xie Case-Control (all) | 222 | 1.32 | 1.04 | 1.68 |
Xie TDT only | 142 | 1.60 | 1.16 | 2.23 |
Present study TOF patients | 595 | 0.91 | 0.78 | 1.08 |
Present study other CVM | 176 | 1.35 | 0.97 | 1.87 |
All studies * | 1341 | 1.04 | 0.93 | 1.16 |
Pooled ORs include the entire population of cases and controls from Xie et al. (2007) rather than the subset of TDT families.