Figure 8.

Comparison of the relative expression of selected downstream effectors of the Notch pathway in nonsmokers (n = 12), normal smokers (n = 15), and smokers with chronic obstructive pulmonary disease (COPD) (n = 13). TaqMan polymerase chain reaction was used to generate the data. Each barrepresents mean expression with standard error; P values are represented in brackets above the bars. Note that the scale is different for Hes1 compared with Hes5, Hey1, and Hey2, reflecting the higher relative level of expression of Hes1 compared with the other downstream effectors.