TABLE 1.
DIFFERENTIALLY REGULATED PROBE SETS (N = 59) BETWEEN 0-HOUR CONTROL MICE AND SEPTIC MICE AT 24- AND 48-HOUR STATUS AFTER CECAL LIGATION AND PUNCTURE
| Affymetrix Probe Set ID | 24-h Fold Change | 48-h Fold Change | Genbank ID | Gene Symbol | Gene Name |
|---|---|---|---|---|---|
| 1427747_a_at | 1593.0 | 540.1 | X14607 | Lcn2 | lipocalin 2 |
| 1440865_at | 276.4 | 202.3 | BB193024 | Ifitm6 | interferon-induced transmembrane protein 6 |
| 1419764_at | 189.6 | 181.6 | NM_009892 | Chi3l3 | chitinase 3-like 3 |
| 1442339_at | 185.7 | 606.5 | BB667930 | MGI:3524944 | stefin A2 like 1 |
| 1417898_a_at* | 156.7 | 549.6 | NM_010370 | Gzma | granzyme A |
| 1418809_at | 153.0 | 530.7 | NM_011087 | Pira1 | paired-Ig-like receptor A1 |
| 1449984_at | 137.5 | 206.3 | NM_009140 | Cxcl2 | chemokine (C-X-C motif) ligand 2 |
| 1451563_at | 128.4 | 1831.0 | AF396935 | Emr4 | EGF-like module containing, mucin-like, hormone receptor-like sequence 4 |
| 1456250_x_at | 126.3 | 324.6 | BB533460 | Tgfbi | transforming growth factor, beta induced |
| 1422013_at | 120.3 | 759.8 | NM_011999 | Clec4a2 | C-type lectin domain family 4, member a2 |
| 1436530_at | 109.6 | 287.0 | AA666504 | CDNA clone MGC:107680 IMAGE:6766535 | |
| 1450826_a_at | 104.9 | 524.0 | NM_011315 | Saa3 | serum amyloid A 3 |
| 1419394_s_at | 104.6 | 48.6 | NM_013650 | S100a8 | S100 calcium binding protein A8 (calgranulin A) |
| 1424254_at | 98.9 | 86.1 | BC027285 | Ifitm1 | interferon-induced transmembrane protein 1 |
| 1442798_x_at | 93.7 | 104.1 | BB324660 | Hk3 | hexokinase 3 |
| 1456223_at | 93.2 | 246.8 | BF322016 | Transcribed locus | |
| 1416635_at | 83.0 | 683.2 | NM_020561 | Smpdl3a | sphingomyelin phosphodiesterase, acid-like 3A |
| 1437478_s_at | 81.2 | 200.3 | AA409309 | Efhd2 | EF hand domain containing 2 |
| 1422953_at | 77.8 | 62.0 | NM_008039 | Fpr-rs2 | formyl peptide receptor, related sequence 2 |
| 1436202_at | 76.1 | 160.7 | AI853644 | Malat1 | metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) |
| 1419709_at | 71.8 | 314.9 | NM_025288 | Stfa3 | stefin A3 |
| 1450808_at | 68.2 | 125.5 | NM_013521 | Fpr1 | formyl peptide receptor 1 |
| 1430700_a_at | 67.7 | 309.5 | AK005158 | Pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| 1448756_at | 67.5 | 23.5 | NM_009114 | S100a9 | S100 calcium binding protein A9 (calgranulin B) |
| 1420331_at | 65.8 | 251.8 | NM_019948 | Clec4e | C-type lectin domain family 4, member e |
| 1420330_at | 64.9 | 220.2 | NM_019948 | Clec4e | C-type lectin domain family 4, member e |
| 1423346_at | 63.2 | 272.6 | AV286991 | Degs1 | degenerative spermatocyte homolog 1 (Drosophila) |
| 1418722_at | 62.4 | 28.6 | NM_008694 | Ngp | neutrophilic granule protein |
| 1429900_at | 62.0 | 286.4 | BM241296 | 5330406M23Rik | RIKEN cDNA 5330406M23 gene |
| 1434773_a_at | 57.7 | 137.9 | BM207588 | Slc2a1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| 1420671_x_at | 57.0 | 413.4 | NM_029499 | Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C |
| 1419598_at | 55.4 | 276.6 | NM_026835 | Ms4a6d | membrane-spanning 4-domains, subfamily A, member 6D |
| 1421392_a_at | 53.8 | 140.5 | NM_007464 | Birc3 | baculoviral IAP repeat-containing 3 |
| 1418189_s_at | 53.2 | 197.8 | AF146523 | Malat1 | metastasis associated lung adenocarcinoma transcript 1 (noncoding RNA) |
| 1435761_at | 51.2 | 322.8 | AW146083 | Stfa3 | stefin A3 |
| 1419599_s_at | 49.6 | 362.9 | NM_026835 | Ms4a11 | membrane-spanning 4-domains, subfamily A, member 11 |
| 1421408_at | 49.3 | 246.7 | NM_030691 | Igsf6 | immunoglobulin superfamily, member 6 |
| 1418204_s_at | 46.1 | 282.2 | NM_019467 | Aif1 | allograft inflammatory factor 1 |
| 1420394_s_at | 40.3 | 89.0 | U05264 | Gp49a; Lilrb4 | glycoprotein 49 A; leukocyte immunoglobulin-like receptor, subfamily B, member 4 |
| 1416530_a_at | 39.0 | 168.2 | BC003788 | Pnp | purine-nucleoside phosphorylase |
| 1437584_at | 38.8 | 158.8 | BE685667 | Transcribed locus | |
| 1419647_a_at | 38.6 | 109.6 | NM_133662 | Ier3 | immediate early response 3 |
| 1419060_at | 35.2 | 141.3 | NM_013542 | Gzmb | granzyme B |
| 1448123_s_at | 33.9 | 129.3 | NM_009369 | Tgfbi | transforming growth factor, beta induced |
| 1429954_at | 28.7 | 245.8 | AK014135 | Clec4a3 | C-type lectin domain family 4, member a3 |
| 1448061_at | 27.9 | 204.0 | AA183642 | Msr1 | macrophage scavenger receptor 1 |
| 1438943_x_at | 27.7 | 136.2 | AV308148 | Rpn1 | ribophorin I |
| 1439057_x_at | 23.3 | 292.2 | BB143557 | Zdhhc6 | zinc finger, DHHC domain containing 6 |
| 1448620_at | 22.2 | 77.9 | NM_010188 | Fcgr3 | Fc receptor, IgG, low affinity III |
| 1455899_x_at | 21.4 | 88.3 | BB241535 | Socs3 | suppressor of cytokine signaling 3 |
| 1447277_s_at | 20.9 | 630.1 | BB785407 | Pcyox1 | prenylcysteine oxidase 1 |
| 1419209_at | 20.5 | 407.7 | NM_008176 | Cxcl1 | chemokine (C-X-C motif) ligand 1 |
| 1433699_at | 17.7 | 58.8 | BM241351 | Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 |
| 1455908_a_at | 16.3 | 212.3 | AV102733 | Scpep1 | serine carboxypeptidase 1 |
| 1457666_s_at | 14.8 | 67.8 | AV229143 | Ifi202b | interferon activated gene 202B |
| 1427076_at | 12.9 | 91.1 | L20315 | Mpeg1 | macrophage expressed gene 1 |
| 1420249_s_at | 8.8 | 94.7 | AV084904 | Ccl6 | chemokine (C-C motif) ligand 6 |
| 1416382_at | 6.1 | 101.0 | NM_009982 | Ctsc | cathepsin C |
| 1449193_at | 2.5 | 66.9 | NM_009690 | Cd5l | CD5 antigen-like |
*
Cell death (GO:0008219) genes (n = 6) are noted in bold.