Skip to main content
. 2009 Feb 10;64A(3):340–350. doi: 10.1093/gerona/gln054

Appendix 1.

Correlations Between the Serum Melatonin (pg/mL) and Serotonin (ng/mL) Levels and the Locomotor Activity (pulses), and Core and Peripheral Temperatures Under Control Conditions and After a 3-day Administration of 0.25 mg Melatonin/kg of Body Weight (b.w.) and 2.5 mg Melatonin/kg of b.w. to Young and Old Ringdoves, Respectively, 1 Hour Before Lights Off (7 PM), or 300 mg Tryptophan/kg of b.w. to Old Ringdoves 1 hour After Lights On (9 AM)

Pulses of Activity Core Temperature Peripheral Temperature
Serum melatonin (pg/mL) Control young animals y = −0.4x + 176.4; R2 = .77 (–); p < .000; f.d. = 12 y = −73.8x + 3,162.5; R2 = .62 (–); p < .001; f.d. = 12 y = −42.9x + 1493.6; R2 = .73 (–); p < .000; f.d. = 12
Melatonin-treated young animals y = −2.6x + 1,006.9; R2 = .78 (–); p < .001; f.d. = 8 y = −496.3x + 20,822; R2 = .68 (–); p < .002; f.d. = 9 y = −215.9 + 7,592.3; R2 = .70 (–); p < .001; f.d. = 6
Control old animals y = −0.4x + 129.2; R2 = .90 (–); p < .000; f.d. = 12 y = −84.4x + 3,536.5; R2 = .56 (–); p < .02; f.d. = 7 y = −17.4 + 650.7; R2 = .84 (–); p < .000; f.d. = 8
Melatonin-treated old animals y = −3.9x + 856.7; R2 = .90 (–); p < .000; f.d. = 8 y = −487.4x + 2,0262; R2 = .66 (–); p < .002; f.d. = 9 y = −152.6x + 5,612.9; R2 = .73 (–); p < .002; f.d. = 8
Tryptophan-treated old animals y = −1.0x + 415.3; R2 = .84 (–); p < .000; f.d. = 7 y = −146.5x + 6,249.9; R2 = .64 (–); p < .002; f.d. = 10 y = −68.1x + 2,626.9; R2 = .71 (–); p < .004; f.d. = 7
Serum serotonin (ng/mL) Control young animals y = 0.4x + 1,601.7; R2 = .62 (+); p < .003; f.d. = 10 y = 77.3x − 1,514.3; R2 = .57 (+); p < .002; f.d. = 12 y = 43.1x + 287.5; R2 = .62 (+); p < .001; f.d. = 12
Melatonin-treated young animals y = 0.5x + 1,585.5; R2 = .77 (+); p < .000; f.d. = 9 y = 80.6x − 1,593; R2 = .83 (+); p < .000; f.d. = 12 y = 46.5x + 196.5; R2 = .51 (+); p < .41; f.d. = 5
Control old animals y = 0.4x + 1,506.5; R2 = .62 (+); p < .007; f.d. = 8 y = 143.6x − 4,343.9; R2 = .51 (+); p < .021; f.d. = 8 y = 33.6x + 495.4; R2 = .64 (+); p < .003; f.d. = 9
Melatonin-treated old animals y = 0.5x + 1,516.7; R2 = .84 (+); p < .000; f.d. = 10 y = 88.2x − 2,010.9; R2 = .82 (+); p < .000; f.d. = 9 y = 24.1x + 744.6; R2 = .76 (+); p < .001; f.d. = 8
Tryptophan-treated old animals y = 4.2x + 2,348.5; R2 = .88 (+); p < .000; f.d. = 9 y = 593.6x − 2,1168; R2 = .80 (+); p < .000; f.d. = 9 y = 235.3x − 5,144.5; R2 = .70 (+); p < .002; f.d. = 8

Note: (+) and (−) indicate that there exists a positive or negative correlation, respectively, between the two variables; df = degrees of freedom.