Table 1.
Comparative Analysis of Giant Cell Arteritis Mortality Studies to Date
Study | Year | Number of Patients | Percent Biopsy Proven | Primary Method of Analysis | Unit Time | Findings |
Hauser and colleagues (19) | 1971 | 19 | 63 | Life table | y | No effect |
Huston and colleagues (8) | 1978 | 42 | 90 | Kaplan-Meier | mo | No effect |
Jonasson and colleagues (20) | 1979 | 136 | 100 | Standardized mortality ratio | mo | No effect |
Graham and colleagues (21) | 1981 | 90 | 100 | Life table | mo | Increased mortality in women |
Chuang and colleagues (22) | 1982 | 15 | 93 | Kaplan-Meier | mo | No effect |
Gouet and colleagues (23) | 1985 | 87 | 100 | Life table | y | No effect |
Andersson and colleagues (24) | 1986 | 90 | 72 | Standardized mortality ratio | mo | Increased 5-y survival, no effect at 10 and 15 y |
Nordborg and Bengtsson (18) | 1989 | 284 | 100 | Standardized mortality ratio | mo | No effect |
Bisgård and colleagues (25) | 1991 | 34 | 100 | Standardized mortality ratio | y | Increased mortality |
Nesher and colleagues (26) | 1994 | 43 | 91 | Standardized mortality ratio | mo | Increased mortality |
Matteson and colleagues (27) | 1996 | 205 | Not reported (<100) | Standardized mortality ratio | d | No effect |
García-Porrúa and colleagues (28) | 1996 | 54 | 100 | Standardized mortality ratio | mo | Increased mortality at 5 y, no effect at 10 y |
González-Gay and colleagues (29) | 1997 | 109 | 100 | Standardized mortality ratio | mo | No effect |
Gran and colleagues (30) | 2001 | 42 | 100 | Cox proportional hazard | mo | No effect |
Uddhammar and colleagues (31) | 2002 | 136 | 100 | Standardized mortality ratio | d | Increased mortality in women |
Salvarani and colleagues (32) | 2004 | 173 | 87 | Kaplan-Meier | d | No effect |
Crow and colleagues | 2007 | 44 | 100 | Kaplan-Meier | d | Increased mortality at 5 y |
Note: d = days; mo = months; y = years.