Table 1.
Presence of metabolic risk factors and liver histology (steatosis/necroinflammation) in NASH cases
|
NASH patients (n = 69) |
||||||
|
Fatty infiltration |
Necroinflammation |
|||||
| Mild (%) | Moderate (%) | Severe (%) | Mild (%) | Moderate(%) | Severe (%) | |
| Gender | ||||||
| Male | 37.1 | 40.0 | 22.9 | 31.4 | 62.9 | 5.7 |
| Female | 41.2 | 35.3 | 23.5 | 20.6 | 64.7 | 14.7 |
| Hepatomegaly | ||||||
| (+)1 | 31.3 | 37.5 | 31.2 | 25.0 | 62.5 | 12.5 |
| (-)1 | 38.5 | 38.5 | 23.0 | 27.0 | 61.5 | 11.5 |
| Body mass index | ||||||
| 18.5-24.9 | 0 | 66.6 | 33.4 | 33.4 | 33.3 | 33.3 |
| 25-29.9 | 35.3 | 41.2 | 23.5 | 26.5 | 64.7 | 8.8 |
| 30-39.9 | 46.5 | 25.0 | 28.5 | 28.6 | 57.1 | 14.3 |
| > 40 | 25.0 | 75.0 | 0 | 25.0 | 75.0 | 0 |
| Central obesity | ||||||
| (+) | 38.8 | 40.8 | 20.4 | 26.5 | 63.3 | 10.2 |
| (-) | 35.0 | 30.0 | 35.0 | 30.0 | 55.0 | 15.0 |
| Hypertension | ||||||
| (+) | 33.4 | 33.3 | 33.3 | 19.0 | 62.0 | 19.0 |
| (-) | 39.6 | 39. | 20.8 | 33.3 | 58.3 | 8.4 |
| Diabetes | ||||||
| (+) | 40.0 | 35.0 | 25.0 | 33.4 | 57.1 | 9.5 |
| (-) | 38.7 | 38.7 | 22.6 | 30.7 | 59.1 | 10.2 |
| Hypertriglyceridemia | ||||||
| (+) | 36.2 | 34.0 | 29.8 | 21.4 | 63.8 | 14.8 |
| (-) | 41.0 | 54.5 | 4.5 | 41.0 | 54.5 | 4.5 |
| Insulin resistance | ||||||
| (+) | 33.3 | 36.7 | 30.0 | 13.3 | 73.4 | 13.3 |
| (-) | 43.5 | 34.7 | 21.8 | 47.8 | 43.5 | 8.7 |
1
(+): Present; (-): Absent. Presence of hypertriglyceridemia and insulin resistance seemed to increase the severity of steatosis and necroinflammation but these findings were not significant.