Table 2.
Presence of metabolic risk factors and liver histology (stage) in NASH cases
|
NASH patients (n = 70)1 |
|||||
|
Fibrosis |
Cirrhosis (%) | ||||
| Absent (%) | Perisinusoidal/Pericellular (%) | Periportal (%) | Bridging (%) | ||
| Gender | |||||
| Male | 51.4 | 23.0 | 14.3 | 8.60 | 2.70 |
| Female | 38.2 | 47.0 | 5.9 | 8.90 | - |
| Hepatomegaly | |||||
| (+)2 | 44.1 | 31.2 | 6.3 | 12.5 | 5.90 |
| (-)2 | 44.3 | 36.5 | 13.5 | 7.70 | - |
| Body mass index | |||||
| 18.5-24.9 | 33.3 | 0 | 33.3 | 33.3 | - |
| 25-29.9 | 38.2 | 44.1 | 11.7 | 5.8 | - |
| 30-39.9 | 46.4 | 25.0 | 14.2 | 10.7 | 3.12 |
| > 40 | 25.0 | 75.0 | 0 | 0 | - |
| Central obesity | |||||
| (+) | 46.9 | 30.6 | 16.3 | 6.1 | 2.04 |
| (-) | 65.0 | 20.0 | 10.0 | 5 | - |
| Hypertension | |||||
| (+) | 47.8 | 42.8 | 4.7 | 4.7 | - |
| (-) | 58.4 | 24.4 | 12.7 | 4.5 | 2.04 |
| Diabetes | |||||
| (+) | 28.5 | 38.0 | 14.2 | 14.2 | 4.76 |
| (-) | 53.1 | 25.5 | 12.7 | 8.5 | - |
| Hypertrigly-ceridemia | |||||
| (+) | 50.0 | 25.0 | 15.6 | 9.3 | - |
| (-) | 59.3 | 31.2 | 6.2 | 3.1 | 4.34 |
| Insulin resistance | |||||
| (+) | 53.3 | 36.6 | 13.3 | 3.3 | 3.33 |
| (-) | 65.7 | 18.4 | 10.5 | 2.6 | - |
169 patients with NASH and 1 cirrhotic patient; 2(+): Present; (-): Absent. Presence of diabetes and insulin resistance seemed to increase the severity of fibrosis, but these findings were not significant.