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Clinical and biochemical characteristics of type 1 and type 2 autoimmune hepatitis
| Characteristics | |
| Type 1 AIH | Anti-SMA, anti-ANA and/or anti-SLA |
| Mean age of onset: 10 yr old | |
| Female:Male ratio 3:1 | |
| Higher incidence | |
| Frequently associated with IBD and sclerosing cholangitis | |
| Type 2 AIH | Anti-LKM1 and/or anti-LC1 |
| Mean age of onset: 6.5 yr old | |
| Female:Male ratio 9:1 | |
| Associated with HLA DR3, DR7 and DQB1*0201 | |
| More severe disease | |
| More likely to be resistant to treatment |
