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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Neuroimage. 2008 Oct 7;44(3):653–660. doi: 10.1016/j.neuroimage.2008.09.027

Table 2.

Sensitivity and specificity of imaging parameters with high predictive power (p < 0.20, Wald test) in differentiation of glioblastomas from brain metastases using receiver operating characteristic curve analysis

Parameter ROI Cutoff value Sensitivity Specificity AUC
CE T1 CR 0.84 0.42 0.24 0.33
ER 1.42 0.58 0.44 0.39

ADC(10−3mm2/s) ER 1.07 0.55 0.48 0.57

FA CR 0.10 0.71 0.68 0.72
ER 0.11 0.89 0.80 0.90
IPR 0.16 0.66 0.76 0.74
DPR 0.17 0.68 0.60 0.63

CL CR 0.10 0.47 0.88 0.71
ER 0.09 0.84 0.84 0.90
IPR 0.13 0.66 0.76 0.76

CP CR 0.05 0.92 0.36 0.66
ER 0.09 0.90 0.64 0.80
IPR 0.12 0.76 0.52 0.66
DPR 0.10 0.78 0.48 0.63

Note - CE T1: contrast-enhanced T1 AUC: area under the curve

CR: central region.

ER: enhancing region.

IPR: immediate peritumoral region

DPR: distant peritumoral region