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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Gene Expr Patterns. 2008 Aug 26;9(1):37–42. doi: 10.1016/j.gep.2008.08.003

Figure 4.

Figure 4

Slow-twitch muscle specification and subsequent migration is not required for localization of laminin, Fak and Fn at the MTJ during muscle morphogenesis, however expression is sometimes disrupted. All panels were obtained using a Zeiss ApoTome. Side views, anterior left, dorsal top of 24 hpf embryos.

A: Laminin (yellow) is highly concentrated at the MTJ of wild-type embryos (A, white arrow). In smu embryos, there are frequently gaps in the myotome boundary, and laminin often congregates at these gaps (A1, arrowheads) in addition to the MTJ (A1, arrow).

B: pY397FAK (blue) is concentrated at the MTJ of wild-type embryos (B, white arrow). In smu embryos, pY397FAK concentrates at the MTJ (B1, white arrow) but not at gaps (B1, yellow arrowheads).

C: Fn (green) is concentrated at the lateral MTJ of wild-type embryos (C, white arrow). In smu embryos, Fn concentrates at the MTJ (C1, white arrow) but is sometimes reduced/absent (C1, green arrowhead).