Table 2.

Efficacy and Discontinuation Cox Regression Models

Variable	Beta±SE	P	Hazard Ratio	95% CI
Efficacy models
Full model with interaction
Age, decades	−0.20±0.02	<0.0001	0.82	0.78 to 0.86
Sex, male	−0.68±0.24	0.005	0.51	0.32 to 0.81
Interaction	0.10±0.04	0.006	1.11	1.03 to 1.19
Men only analysis
Age, decades	−0.09±0.03	0.0007	0.91	0.86 to 0.96
Women only analysis
Age, decades	−0.20±0.02	<0.0001	0.82	0.78 to 0.86
Discontinuation models
Full model with interaction
Age, decades	0.22±0.04	<0.0001	1.25	1.17 to 1.34
Sex, male	0.07±0.37	0.84	1.08	0.52 to 2.23
Interaction	−0.04±0.05	0.47	0.96	0.87 to 1.07
Men only analysis
Age, decades	0.19±0.04	<0.0001	1.21	1.11 to 1.30
Women only analysis
Age, decades	0.22±0.04	<0.0001	1.25	1.16 to 1.34