Table 3.
SNP | βa | P | FDR | Adjustment for TG | |
---|---|---|---|---|---|
βa | P | ||||
32 | 0.055 | 1.8 × 10−4 | 0.021 | 0.035 | 1.2 × 10−2 |
1 | 0.042 | 2.8 × 10−4 | 0.021 | 0.043 | <1.0 × 10−4 |
3 | 0.039 | 3.8 × 10−3 | 0.062 | 0.041 | 7.0 × 10−4 |
22 | 0.031 | 6.6 × 10−4 | 0.028 | 0.032 | 2.0 × 10−4 |
18 | 0.028 | 3.0 × 10−3 | 0.062 | 0.032 | 4.0 × 10−4 |
6 | 0.027 | 2.8 × 10−3 | 0.062 | 0.032 | 2.0 × 10−4 |
28 | 0.025 | 2.2 × 10−2 | 0.186 | 0.023 | 2.1 × 10−2 |
16 | 0.019 | 2.9 × 10−2 | 0.221 | 0.024 | 2.7 × 10−3 |
29 | 0.019 | 3.9 × 10−2 | 0.254 | 0.018 | 3.9 × 10−2 |
35 | −0.022 | 3.8 × 10−2 | 0.254 | −0.017 | 8.6 × 10−2 |
19 | −0.023 | 3.3 × 10−2 | 0.230 | −0.028 | 6.2 × 10−3 |
21 | −0.024 | 7.9 × 10−3 | 0.106 | −0.024 | 2.9 × 10−3 |
15 | −0.029 | 7.4 × 10−4 | 0.028 | −0.031 | <1.0 × 10−4 |
4 | −0.030 | 1.5 × 10−2 | 0.137 | −0.028 | 1.9 × 10−2 |
9 | −0.030 | 4.4 × 10−2 | 0.259 | −0.018 | 2.0 × 10−1 |
20 | −0.032 | 1.1 × 10−2 | 0.117 | −0.031 | 6.2 × 10−3 |
Linear-regression analysis of SNP association with log HDL-C. SNPs are listed by descending estimate (β). Estimates represent percent change in HDL-C. Adjustment for TG means that associations were corrected for an effect of triglyceride levels. FDR, false discovery rate.
a±SE <0.01 for all estimates with the exception of SNP 9 where ± SE = 0.02.