FIGURE 2.

HA does not block cathelicidin-induced IL-8 release in keratinocytes. NHEKs were pretreated with 25 μg/ml HA for 1 h, followed by stimulation with 3 μM or 10 μM LL-37 for 24 h. IL-8 in culture supernatants was measured by ELISA. Mean ± S.D. (**, p < 0.01 vs non LL-37-stimulated cells, n = 4). n.s., not significant.