Table 1.
Night CSF sample group: means ± standard deviations and statistical comparisons between groups. * indicates significant difference (p<0.05) from control and ** indicate significant difference between High and normal 3OMD. ANOVA is used for the comparison for all groups with pair-wise comparisons using FPLSD. The PLMS/hr and JHRLSS are only compared between normal and high 3OMD using t test.
Normal controls | RLS | ANOVA/ t test | ||
---|---|---|---|---|
Normal 3OMD | High 3OMD | F/t, p | ||
Sample size | 22 | 15 | 17 | |
age | 59.2 ± 8.3 | 59.7 ± 9.4 | 65.6 ±9.7* | F= 2.7, p=0.07 |
Male:Female | 11:11 | 6:9 | 10:7 | ChiSqr=1.1, p=0.29 |
CSF HVA (nmol/l) | 216.9 ±88.3 | 177.7 ±106.7 | 296.8 ±126.4*, ** | F=5.3, p=0.008 |
CSF 5HIAA (nmol/l) | 98.0 ±33.7 | 85.1 ±41.1 | 136.4 ±47.8 *, ** | F=7.2, p=0.002 |
CSF ferritin (mcg/l) | 2.89 ±0.91 | 2.65 ±0.77 | 2.31 ±0.69 * | F=2.39, p=0.10 |
PLMS/hr | 5.4 ±5.0 | 66.8 ±49.9 | 106.6 ±56.9 ** | t=1.95, p=0.03 |
JHRLSS | ------ | 1.73 ±0.46 | 1.82 ±0.73 | t=0.43, p=ns |