Table 2.
Day CSF sample group: means ± standard deviations and statistical comparisons between groups. * indicates significant difference (p<0.05) from control and ** indicate significant difference between High and normal 3-OMD. ANOVA is used for the comparison for all groups with pair-wise comparisons using FPLSD. The JHRLSS are only compared between normal and high 3OMD groups using t test. Gender information was unavailable for normal controls.
| Normal controls | RLS | ANOVA/ t test | ||
|---|---|---|---|---|
| Normal 3OMD | High 3OMD | F/t, p | ||
| Sample size | 14 | 4 | 13 | |
| age | 51.4 ± 14.8 | 58.0 ± 14.2 | 65.3 ± 9.6* | t=1.2, p=0.25 |
| Male:Female | *** | 4:0 | 10:3 | ChiSqr=1.2, p=0.29 |
| CSF HVA (nmol/l) | 233.3 ±49.2 | 152.5 ± 64.6* | 246.4 ± 71.1*, ** | F=3.7, p=0.038 |
| CSF 5HIAA (nmol/l) | 107.22 ± 22.6 | 55.6 ± 43.8* | 99.9 ± 33.5** | F=4.6, p=0.019 |
| CSF ferritin (mcg/l) | 3.5 ± 1.56 | 0.61 ± 0.24* | 1.36 ±1.11* | F=10.6, p=0.0006 |
| JHRLSS | 2.0 ±1.16 | 2.3 ±0.77 | t=0.78, p=0.45 | |