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. 1992 Sep;30(9):2498–2501. doi: 10.1128/jcm.30.9.2498-2501.1992

Spectrum of monoclonal antibodies to coxsackievirus B-3 includes type- and group-specific antibodies.

S Yagi 1, D Schnurr 1, J Lin 1
PMCID: PMC265534  PMID: 1328290

Abstract

Fifteen monoclonal antibodies (MAbs) made to coxsackievirus B-3 were tested against a panel of enteroviruses by indirect immunofluorescence. The MAbs included seven which reacted with coxsackievirus B-3 only, five which reacted with more than one enterovirus included in the panel, one which reacted with broad enteroviral specificity and did not react with any heterologous virus (group specific), and two which reacted with all enteroviruses tested and at least one heterologous virus. The group-specific MAb identified 44 of 45 clinical isolates as enteroviruses, while the two broadly reactive MAbs reacted with all 45 of the clinical isolates. These MAbs are potentially important diagnostic reagents for grouping and typing enteroviruses by indirect immunofluorescence.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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