Table 8.
Myocardium-to-Non-target Tissue Ratios in Rats, Based on Radiotracer Biodistribution Calculated as a Percentage of the Injected Dose per Gram Tissue Wet Mass.
| Heart/Blood |
Heart/Lung |
Heart/Liver |
||||
|---|---|---|---|---|---|---|
| Radiopharmaceutical | 1 min | 2 hrs | 1 min | 2 hrs | 1 min | 2 hrs |
| [67Ga][Ga-1]1+ | 6.5 ± 0.3 | 33.8 ± 4.9 | 2.13 ± 0.12 | 2.8 ± 0.4 | 1.13 ± 0.09 | 10.9 ± 2.2 |
| [67Ga][Ga-2]1+ | 4.0 ± 0.4 | 23.3 ± 2.7 | 1.97 ± 0.29 | 2.6 ± 0.3 | 1.0 ± 0.2 | 7.2 ± 0.8 |
| [67Ga][Ga-3]1+ | 0.68 ± 0.08 | 6.4 ± 1.3 | 0.58 ± 0.04 | 1.58 ± 0.08 | 0.33 ± 0.02 | 2.7 ± 0.3 |
| [67Ga][Ga-4]1+− | 7.6 ± 1.0 | 54 ± 10 | 1.85 ± 0.17 | 2.9 ± 0.4 | 1.8 ± 0.4 | 39.0 ± 3.0 |
| [67Ga][Ga-5]1+ | 1.86 ± 0.08 | 37.9 ± 3.5 | 1.00 ± 0.05 | 2.4 ± 0.3 | 0.85 ± 0.22 | 7.2 ± 1.9 |
| [99mTc]Tc-Sestamibi1+* | 11.1 ± 0.2 | 208 ± 25† | 1.3 ± 0.2 | 6.5 ± 1.7† | 1.7 ± 0.1 | 5.3 ± 1.7† |
From reference 11.
Data from 60-minutes rather than 120-minutes post-injection.