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. Author manuscript; available in PMC: 2009 Sep 24.
Published in final edited form as: J Am Chem Soc. 2008 Sep 3;130(38):12636–12638. doi: 10.1021/ja801510d

Table 1.

Calculated dissociation constants (nM) of aptamers with fibrinogen and glycan-modified fibrinogen*

Aptamer Fibrinogen Deglycosylated Fibrinogen Periodated fibrinogen
B-TTP TTP B-TTP TTP B-TTP TTP
85A 6.2±1.4 102±39.7 390±145 60.2±18.0 70.7±18.4 67.4±25.0
85B 6.4±0.81 63.8±16.
9		 86.2±16.4 140±15.9 118±17.0 130.2±18.
7
85C 17.1±2.1 122±43.7 371±61.9 256±28.9 202±28.1 321±39.7
*

All studies were done in triplicate.