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. 2008 Oct;143(2):288–293. doi: 10.1111/j.1365-2141.2008.07335.x

Table I.

Percentage distribution of Duffy (Fy) blood group system-associated SNPs by country of origin, ANC, cytokines, and ELA2rs57834246 allele status.

CC TC TT
N (n = 121), % (n = 66), % (n = 69), % P-value
Country (race)
 Barbados/Trinidad-Tobago 45 69 20 11 0·0001
 Dominican Republic 50 8 40 52
 Haiti 49 75 25 0
 Jamaica 35 63 37 0
 United States (black) 37 73 27 0
 United States or Europe (white) 40 0 5 95
 Overall 256 47 26 27
Median ANC (×109/l) 2684 4212 3953 <0·0001
% ANC ≤ 1500 × 109/l 4·4 9·3 0 0 0·001
TNF-α (pg/ml)
 Non-detectable 134 48·5 28·4 23·1 0·65
 ≤233·3 63 47·6 22·2 30·2
 >233·3 59 44·1 23·7 32·2
G-CSF (ng/ml)
 <0·0259 85 32·9 27·1 40·0 0·002
 0·026–0·0381 82 47·6 24·4 28·0
 >0·0381 84 59·5 26·2 14·3
CRP (μg/ml)
 <1·54 116 44·0 25·9 30·2 0·84
 1·55–5·67 66 29·3 22·7 25·8
 >5·67 64 46·9 28·1 25·0
ELA2 rs57834246 genotype
 CC 168 36·3 25·6 38·1 0·0001
 CA or AA 75 69·3 24·0 6·7

ANC, absolute neutrophil count; SNPs, single nucleotide polymorphisms; CRP, C-reactive protein; G-CSF, granulocyte colony-stimulating factor; TNF-α, tumour necrosis factor-alpha.