Figure 4. The effects of treatment with the antiprogestin RU486 on EC50 and maximal response parameters for OT.
The data were obtained using uterine strips from rats at gestational day 16 following 24 h treatment with placebo (grey bars; n = 5) or RU486 (stippled bars; n = 18). For comparison, data are also presented for rats at day 21 or 22 in active labour (black bars; n = 9 or 10). Bars with unique superscripts are significantly different from bars without overlapping superscripts.