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. 2008 Oct 20;586(Pt 24):5911–5929. doi: 10.1113/jphysiol.2008.163154

Figure 6. Effect of elevation of cAMP on properties of Ih in rat DRG neurons of different sizes.

Figure 6

A, B, C and D show properties of activation of Ih in rat large (A), medium fast (MF, B), medium slow (MS, C) and small DRG neurons (D). Upper panels show representative current traces in response to a voltage pulse from −60 mV to −90 mV in the absence (•) and presence (○) of 50 μm FK. Middle panels show steady-state activation curves of Ih as a function of membrane voltage over the range −120 mV to −40 mV in the absence (•) and presence (○) of 50 μm FK. Lower panels show τf in absence (•) and presence (○) of 50 μm FK. E, effect of 50 μm FK on values of V½ in the four populations of rat DRG neurons shown in A–D. Absence and presence of 50 μm FK is shown by filled or open symbols, respectively. Experiments repeated n = 10–15 times in each neuronal population.