FIG. 2.
The rad50S mutant is proficient for meiotic recombination and meiosis-specific nucleosome remodeling, but both functions are defective in the rad50Δ mutant. (a) Meiotic intergenic recombination levels in surviving rad50Δ spores were strongly reduced at different genetic intervals at both 25°C and 34°C. However, the rad50S strain was proficient for recombination at both temperatures. (b) Meiosis-specific nucleosome remodeling at ade6-M26 (see black arrow for the WT at 3 h) was defective at 34°C in the rad50Δ strain (and the rad32mre11Δ mutant), whereas the rad50S strain was proficient.