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(a) A ctp1 deletion mutant is deficient in removing Rec12Spo11 from the DNA in meiotic cells. The defect is comparable to that of rad50S and rad32mre11-D65N strains. (b) Meiotic spore viability is strongly reduced in the ctp1Δ strain, similar to that of the rad32-D65N strain. (c) The ctp1Δ strain is proficient for ade6-M26 chromatin remodeling (black arrow).
