FIG. 10.
Differential effects of TSA treatment on CD69 and heparanase transcript kinetics. (A and B) Heparanase and CD69 mRNA kinetics were measured by TaqMan real-time PCR with resting (NS) Jurkat T cells and cells stimulated with PI for the times indicated. mRNA levels are expressed as n-fold changes relative to NS samples. For TSA treatment, cells were preincubated with TSA for 5 h and then stimulated for the times indicated. Transcript induction kinetics are shown for heparanase (A) and CD69 (B). Data shown are the mean ± the standard error of three replicate experiments.
