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Temperature dependence of the binding enthalpy for 2-amino-1,8-naphthyridine-cytosine interactions: (a) AND and (b) ATMND. Errors are the standard deviations obtained from at least three independent measurements. The linear least squares fit to the data yielded the heat capacity change, ΔCp, of –161 cal/mol K for AND (r = 0.9906), and –217 cal/mol K for ATMND (r = 0.9999), respectively. See Table 2 for further details.
