. 2009 Mar 25;4(3):e4948. doi: 10.1371/journal.pone.0004948

Table 1. Measles Virus-induced activation of lymphocytes in CD150 transgenic mice.

Percentage of positive cells^*		Control		CD150 tg
		Uninfected	Infected	Uninfected	Infected
CD4⁺		13,33±2,31	13,75±1,81	15,56±2,46	34,36±14,71^**
CD4⁺	CD69⁺	2,77±0,44	3,51±0,40	3,37±0,76	8,93±2,39^***
CD4⁺	CD62L⁺	86,55±2,57	83,63±1,45	83,60±2,89	71,42±11,42
CD4⁺	CD44^high	9,57±1,37	9,05±0,93	7,27±0,31	8,67±0,88
CD4⁺	CD25⁺Foxp3⁺	7,27±0,78	7,08±0,38	7,27±0,35	10,02±1,20^***
CD8⁺		4,74±0,79	4,58±1,26	6,24±1,86	13,95±5,14^**
CD8⁺	CD69⁺	2,08±0,46	2,53±0,42	2,90±1,10	10,05±6,87^**
CD8⁺	CD62L⁺	76,88±4,15	83,18±2,17	73,78±3,84	60,54±8,24^**
CD8⁺	CD44^high	16,30±1,08	16,27±2,06	15,73±3,09	9,59±5,95
CD19⁺		63,07±4,24	71,95±4,20	53,58±13,64	38,02±16,71
CD19⁺	CD69⁺	1,83±0,22	2,11±0,23	2,33±0,92	9,77±5,60^**
CD19⁺	CD80⁺	1,43±0,13	1,46±0,56	1,20±0,15	2,77±0,83

Mice were inoculated intranasally with either MV (500 to 1000 PFU) or with medium (uninfected). Splenocytes were prepared 13 days post-infection, stained with indicated antibodies and analyzed by flow cytometry. Results are expressed as the mean percentage (+/−SD) of positive cells (CD69⁺, CD62L⁺, CD44^high or CD80⁺) in a given cell subset (CD4⁺, CD8⁺ or CD19⁺) (4 to 6 mice per group). These results are from one experiment representative out of three.

^**

p<0.05.

^***

p<0.01, Student t-test, calculated between CD150 infected and noninfected mice.