Table 2.
Association between methylation of ATM mvp2b and phenotypic data from the bilateral breast cancer patients and controls reveals an association between methylation and age in cases but not in controls
| Cases, median (range) | Cases, P-valuea | Cases, P-adjustedb | Controls, median (range) | Controls, P-valuea | Controls, P-adjustedb | |
|---|---|---|---|---|---|---|
| Age at blood draw | 62.8 (37.5–79.6) | 0.00109** | 0.01035** | 62.8 (37.1–79.4) | 0.106 | 0.4028 |
| Age at first diagnosis | 47 (26–64) | 0.0145** | 0.0918 | NA | NA | NA |
| Age at second diagnosis | 56 (26–70) | 0.000487** | 0.0093** | NA | NA | NA |
| Time between diagnoses | 6 years (0–26) | 0.177 | 0.4204 | NA | NA | NA |
NA, not applicable.
aLinear model regression.
bFDR corrected for multiple testing.
**Signifies significant association (P < 0.05).