Fig. 3.

Plasma protein carbonyl levels are increased in subjects with organic acidemias. Plasma carbonyl levels were measured in 100 μL of platelet-free plasma as described in Materials and Methods. Statistical significance was determined by Wilcoxon/Kruskal Wallis non-parametric test for ranked sums using JMP software. Each point represents a single subject. Solid circles represent subjects not on antioxidants and open circles represent subjects on antioxidants. Adult controls (n = 10): subjects with mitochondrial disorders (n = 12); and subjects with organic acidemias (n = 8).