Table 1.
P1 | P2 | P3 | P4 | P5 | P6 | P7 | P8 | P9 |
A | A | E | ||||||
F | P | D | ||||||
L | F | Q | ||||||
I | S | P | ||||||
P | V | N | ||||||
S | L | I | ||||||
V | N | |||||||
R |
The anchor motif of I-Aq would exist at P1, P4 and P7, therefore we predicted the binding motif from amino acid sequences of I-Aq restricted epitopes on murine RNase90–105, myelin basic protein89–101, chicken type II collagen181–209, rat type II collagen256–270, bovine type II collagen256–270 and mouse type II collagen.