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. 2008 Nov 25;10(6):R137. doi: 10.1186/ar2560

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Copyright © 2008 Nguyen et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Redefining the boundaries for the Aec2 Sjögren Syndrome (SjS) susceptibility genetic locus. Based on the disease profiling of the C57BL/6.NOD-Aec1Aec2R(n) recombinant inbred (RI) lines, the boundaries of the Aec2 genetic region containing SjS susceptibility genes have been temporarily reset to position 79 ± 5 cM of chromosome 1 (shaded gray gradient rectangular box). Possible quantitative trait loci genes may reside a few centimorgans centromeric to this region (unshaded rectangular box).