Table 3.
Bivariate relations between tumours and predictors—results from logistic regression models and receiver operating characteristic curve analysis
| Factor | Equal weights to Sensitivity and Specificity | Specificity = 100% | Sensitivity = 100% | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| source | hormone | n | Optimal cut-point | Sensitivity | Specificity | c statistic | p-value* | Cut-point | Sensitivity at cut-point | Cut-point | Specificity at cut-point |
| nmol/L | nmol/L | nmol/L | |||||||||
| Peripheral | T | 136 | 4.51 | 93.8% | 77.8% | 0.91 | <0.001 | 23.94 | 24.6% | 1.70 | 19.4% |
| Ovarian, Right | T | 72 | 26.96 | 67.4% | 73.1% | 0.77 | 0.07 | 505.79 | 21.7% | 4.13 | 7.7% |
| Ovarian, Left | T | 99 | 7.32 | 91.5% | 48.1% | 0.69 | 0.3 | 727.90 | 6.4% | 2.26 | 17.3% |
| Ovarian Maximum | T | 110 | 14.82 | 92.9% | 57.4% | 0.82 | 0.01 | 554.33 | 21.4% | 4.51 | 29.6% |
| Ovarian Average | T | 110 | 15.72 | 83.9% | 64.8% | 0.81 | 0.02 | 1003.35 | 14.3% | 3.99 | 25.9% |
| Adrenal, Right | T | 47 | 5.86 | 87.0% | 70.8% | 0.79 | 0.21 | 39.42 | 4.3% | 3.09 | 50.0% |
| Adrenal, Left | T | 78 | 7.04 | 71.4% | 70.0% | 0.73 | 0.14 | 45.21 | 3.6% | 2.19 | 14.0% |
| Peripheral | A | 89 | 21.08 | 15.0% | 98.0% | 0.53 | 0.11 | 22.41 | 15.0% | 0.45 | 0.0% |
| Ovarian, Right | A | 44 | 2522.43 | 8.3% | 100.0% | 0.33 | 0.51 | 2522.43 | 8.3% | 2.93 | 0.0% |
| Ovarian, Left | A | 71 | 20.80 | 70.4% | 63.6% | 0.67 | 0.75 | 0.98 | 0.0% | 2083.25 | 0.0% |
| Ovarian Maximum | A | 81 | 1028.61 | 8.8% | 97.9% | 0.43 | 0.27 | 1877.97 | 8.8% | 2.83 | 4.3% |
| Ovarian Average | A | 81 | 628.93 | 11.8% | 97.9% | 0.41 | 0.30 | 1218.81 | 8.8% | 2.83 | 4.3% |
| Adrenal, Right | A | 30 | 33.68 | 75.0% | 38.9% | 0.50 | 0.51 | 5.17 | 8.3% | 101.70 | 5.6% |
| Adrenal, Left | A | 61 | 21.85 | 66.7% | 67.4% | 0.66 | 0.16 | 2.83 | 6.7% | 136.21 | 8.7% |
| Peripheral | F | 53 | 270.38 | 87.0% | 70.0% | 0.83 | 0.002 | 662.2 | 13.0% | 118.6 | 13.3% |
| Ovarian, Right | F | <30 | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ |
| Ovarian, Left | F | 39 | 386.26 | 53.8% | 92.3% | 0.75 | 0.02 | 496.6 | 46.2% | 99.3 | 0.0% |
| Ovarian Maximum | F | 44 | 496.62 | 64.3% | 100.0% | 0.80 | 0.004 | 524.2 | 57.1% | 99.3 | 0.0% |
| Ovarian Average | F | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ |
| Adrenal, Right | F | <30 | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ | ~ |
| Adrenal, Left | F | 47 | 7424.47 | 18.2% | 100.0% | 0.54 | 0.20 | 7424.5 | 18.2% | 146.2 | 5.6% |
*
from logistic regression models of ovarian tumours on hormone levels