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. 2009 Jan 13;85(4):617–626. doi: 10.1189/jlb.1008588

Fig. 2.

Fig. 2.

MMP-9 null macrophages display reduced fusion. Representative phase-contrast images of WT (A) and MMP-9 null macrophages (B) at Day 3 showing reduced elongation and FBGC formation in the latter. (A and B) Arrows and arrowheads denote elongated cells and FBGC, respectively. Original bars = 25 μm. (C–E) Analysis of fusion at Day 7 by enumeration of various parameters in May-Grunwald-stained cultures revealed a fusion defect in MMP-9 null macrophages that involved the formation of smaller FBGCs. *, P ≤ 0.05; n = 9. (F) Histogram demonstrating the distribution of nuclei per FBGC.