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. Author manuscript; available in PMC: 2009 Mar 16.
Published in final edited form as: Neuroscience. 2005;130(2):383–388. doi: 10.1016/j.neuroscience.2004.09.012

Fig. 2. In vitro cleavage of mPer1 RNA.

Fig. 2

(A) For DNAzyme cleavage of an in vitro transcript, 4 pmol of a 706-nt mPer1 mRNA transcript were digested with 50 pmol of DNAzyme. The expected 255-nt and 451-nt cleavage products were generated. (B) The control ODN did not show any enzymatic activity. The substrate and cleavage products were separated and analyzed on a urea denaturing polyacrylamide gel.