Table 1.

Rawlins' classification system of ADRs

Type	Definition
A	Dose-dependent ADRs related to the pharmacological effect of the drug:
	• Increased pharmacological effect
	• ADRs that occur secondarily to the desired pharmacological effect
	• ADRs due to other well known pharmacological effects
B	Sensitivity reactions – not dose-dependent
	• Allergic reactions
	• Idiosyncratic reaction
C	Long-term ADRs
	• Carcinogines
	• Teratogenes
	• Chronic organ damage
D	Drug-drug interactions
	• Pharmacodynamic
	• Pharmacokinetic
	• Non-classifiable