Table 5.
Incidence of AOM and TMP in vaccinated and comparison groups, including sensitivity analyses
| AOM | TMP | |||||||
| Baseline analysis | Sensitivity analysis | Baseline analysis | Sensitivity analysis | |||||
| Vaccinated | Comparison | Vaccinated | Comparison | Vaccinated | Comparison | Vaccinated | Comparison | |
| No. of participants | 90 | 37 | 97 | 51 | 94 | 41 | 97 | 51 |
| Examinations per year | 11.53 | 11.80 | 10.24 | 10.20 | 10.77 | 11.70 | 10.03 | 10.20 |
| No. of episodes | 104 | 45 | 139 | 87 | 35 | 23 | 37 | 33 |
| No. with 0 episodes (%) | 29 (32) | 9 (24) | 24 (25) | 6 (12) | 70 (74) | 30 (73) | 71 (73) | 34 (67) |
| No. with 1 episode (%) | 28 (31) | 14 (38) | 28 (29) | 17 (33) | 16 (17) | 3 (7) | 18 (19) | 6 (12) |
| No. with >1 episodes (%) | 33 (37) | 14 (38) | 44 (45) | 28 (55) | 8 (8) | 8 (19) | 8 (8) | 11 (22) |
| Unadjusted incidence | 1.87/yr | 2.05/yr | 1.68/yr | 2.02/yr | 0.55/yr | 0.82/yr | 0.44/yr | 0.77/yr |
| Adjusted incidence* | 1.83/yr | 2.03/yr | 1.62/yr | 2.02/yr | 0.47/yr | 0.75/yr | 0.39/yr | 0.75/yr |
| Absolute rate reduction† | -0.20/yr | -.40/yr | -0.28/yr | -0.36/yr | ||||
* Adjusted in multivariate poisson model considering repeated events.
† Absolute rate reduction is the incidence in the vaccinated minus incidence in the comparison group.
Baseline analyses of incidence of AOM and TMP included participants if the first examination was at less than 4 months and less than 6 months respectively, and included follow-up data if repeated examinations were less than 2 months apart. Sensitivity analyses included participants with any age at first examination, and included follow-up data if repeated examinations were less than 4 months apart.