Table 6.
Pathogens isolated from new tympanic membrane perforations
| Perforation pathogen category |
Vaccinated N = 97 (194 ears) |
Comparison N = 51 (102 ears) |
| New perforations | 73 (38% of ears) | 72 (71% of ears) |
| New perforation discharge specimen collected | 59/73 (81% new perforations) | 44/72 (61% new perforations) |
| Positive discharge specimens* | 32/59 (54% specimens) | 25/44 (57% specimens) |
| S. pneumoniae | 19/32 (59% positive specimens) | 16/25 (64% positive specimens) |
| All vaccine-types | 7 (22%) | 8 (32%) |
| Serotype 6B | 2 (3%) | 5 (20%) |
| All vaccine-related types | 6 (19%) | 2 (8%) |
| Serotype 19A | 4 (13%) | 2 (8%) |
| All non-vaccine types | 9 (28%) | 6 (24%) |
| Serotype 16F | 4 (13%) | 2 (8%) |
| H. influenzae | 28 (88%) | 21 (84%) |
| M. catarrhalis | 0 (0%) | 2 (8%) |
| S. pneumoniae & H. influenzae† | 15 (47%) | 12 (48%) |
* Isolation of S. pneumoniae, H. influenzae or M. catarrhalis.
† Cases of co-infections of H. influenzae and S. pneumoniae have also been included in the numbers for individual pathogens.
Other serotypes isolated: vaccinated group 19F (3), 6A (2), 7C (2), 23F, 3, 7F, 1 & 19F co-isolated. comparison group 23F (2), 11A (2), 9V, 7F, 13.