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. 2001 Feb 17;322(7283):387. doi: 10.1136/bmj.322.7283.387

Table 4.

Mean (95% confidence interval) scores on hospital anxiety and depression scale and sleep problem questionnaire at baseline and follow up at three, six, and 12 months

Control group Minimum intervention Telephone intervention Maximum intervention P value*
Depression
 Baseline 10.4 (8.9 to 11.8)  9.3 (8.0 to 10.5)  9.0 (7.8 to 10.2)  9.0 (7.8 to 10.2)
3 months 11.2 (9.6 to 12.9) 6.1 (4.7 to 7.4) 5.9 (4.5 to 7.3) 5.8 (4.8 to 6.9)
6 months 11.0 (9.2 to 12.9) 5.4 (3.9 to 6.9) 5.6 (4.3 to 6.9) 5.0 (3.8 to 6.2)
1 year 10.1 (8.4 to 11.7) 4.2 (3.0 to 5.5) 4.6 (3.2 to 6.0) 4.2 (2.9 to 5.5) <0.001
Anxiety
 Baseline 11.2 (9.6 to 12.8) 10.6 (9.1 to 12.1) 10.0 (8.4 to 11.7) 10.2 (8.8 to 11.7)
3 months 11.4 (9.8 to 13.1)  9.2 (7.3 to 10.7) 7.7 (6.1 to 9.2)  8.7 (7.2 to 10.1)
6 months 10.6 (8.8 to 12.4)  8.7 (7.1 to 10.2) 7.5 (6.0 to 9.0) 7.7 (6.2 to 9.2)
1 year 10.1 (8.4 to 11.7) 7.1 (5.8 to 8.5) 6.5 (5.1 to 7.9) 7.7 (6.1 to 9.3) <0.01
Sleep problem questionnaire
 Baseline 12.8 (11.1 to 14.5)  12.4 (10.8 to 14.0)  13.5 (12.1 to 15.0)  13.0 (11.4 to 14.7)
3 months 11.6 (9.8 to 13.5)  9.0 (7.4 to 10.5) 10.1 (8.2 to 11.9)  8.7 (7.2 to 10.3)
6 months 12.1 (10.1 to 14.1) 7.4 (5.7 to 9.1)  9.1 (7.2 to 11.0) 8.2 (6.6 to 9.9)
1 year 11.5 (9.7 to 13.4) 6.7 (5.0 to 8.4)  8.6 (6.8 to 10.3) 7.1 (5.6 to 8.7) <0.001
*

P values derived from one way analysis of covariance on scores at one year with initial scores and depression scores as covariates. 

Hospital anxiety and depression scale: score range 0-21, where more than 10 indicates clinical depression or anxiety. 

Score range 0-20, where 20 indicates maximum sleep problems.