Table 4. Association between Selected Polymorphisms and Renal Cancer Risk.
| SNP/Genotypes | Cases | Controls | OR1 | 95% CI | p-trend | |
| CASP 1/5/4/12 | ||||||
| CASP1 | ||||||
| rs1785883 (*12058T>C) | ||||||
| GG | 686 | 880 | 1.00 | |||
| AG | 85 | 145 | 0.75 | 0.56 | 1.00 | |
| AA | 2 | 8 | 0.34 | 0.07 | 1.60 | 0.02 |
| AG+AA | 0.75 | 0.57 | 1.00 | |||
| rs508760 (*12353A>C) | ||||||
| GG | 658 | 893 | 1.00 | |||
| GT | 112 | 135 | 1.12 | 0.85 | 1.47 | |
| TT | 4 | 6 | 1.05 | 0.29 | 3.81 | 0.45 |
| GT+TT | 1.13 | 0.87 | 1.48 | |||
| rs7934239 (−12676T>C) | ||||||
| GG | 700 | 940 | 1.00 | |||
| AG | 74 | 90 | 1.11 | 0.80 | 1.54 | |
| AA | 2 | 2 | 1.27 | 0.18 | 9.10 | 0.50 |
| AG+AA | 1.09 | 0.79 | 1.50 | |||
| rs501626 (−12291A>G) | ||||||
| TT | 580 | 820 | 1.00 | |||
| CT | 183 | 199 | 1.30 | 1.04 | 1.64 | |
| CC | 14 | 16 | 1.19 | 0.57 | 2.48 | 0.03 |
| CT+CC | 1.29 | 1.04 | 1.62 | |||
| rs11821722 (−11804G>A ) | ||||||
| TT | 396 | 548 | 1.00 | |||
| CT | 310 | 405 | 1.09 | 0.89 | 1.33 | |
| CC | 70 | 81 | 1.21 | 0.85 | 1.71 | 0.23 |
| CT+CC | 1.11 | 0.92 | 1.34 | |||
| rs568910 (IVS2+365T>G) | ||||||
| AA | 518 | 744 | 1.00 | |||
| AC | 225 | 254 | 1.28 | 1.03 | 1.59 | |
| CC | 31 | 35 | 1.24 | 0.75 | 2.05 | 0.03 |
| AC+CC | 1.28 | 1.05 | 1.57 | |||
| CASP5 | ||||||
| rs492859 (−5645T>G) | ||||||
| CC | 514 | 741 | 1.00 | |||
| AC | 227 | 251 | 1.31 | 1.06 | 1.62 | |
| AA | 30 | 35 | 1.21 | 0.73 | 2.00 | 0.02 |
| AC+AA | 1.29 | 1.05 | 1.58 | |||
| rs3181318 (−373 C>T) | ||||||
| GG | 337 | 472 | 1.00 | |||
| AG | 349 | 457 | 1.09 | 0.90 | 1.33 | |
| AA | 89 | 106 | 1.20 | 0.88 | 1.65 | 0.21 |
| AG+AA | 1.12 | 0.93 | 1.35 | |||
| rs507879 (Ex2-118A>G, T90A) | ||||||
| TT | 212 | 337 | 1.00 | |||
| CT | 381 | 481 | 1.29 | 1.03 | 1.60 | |
| CC | 179 | 209 | 1.39 | 1.07 | 1.82 | 0.01 |
| CT+CC | 1.31 | 1.07 | 1.61 | |||
| EGFR | ||||||
| rs11977660 (IVS1-47643T>C) | ||||||
| TT | 220 | 285 | 1.00 | |||
| CT | 381 | 499 | 0.98 | 0.79 | 1.23 | |
| CC | 176 | 251 | 0.88 | 0.68 | 1.15 | 0.37 |
| CT+CC | 0.95 | 0.77 | 1.17 | |||
| rs6593205 (IVS1-41287A>G) | ||||||
| GG | 310 | 414 | 1.00 | |||
| AG | 368 | 456 | 1.09 | 0.89 | 1.34 | |
| AA | 98 | 164 | 0.80 | 0.60 | 1.07 | 0.37 |
| AG+AA | 1.02 | 0.84 | 1.23 | |||
| rs6954351 (IVS1-38789G>A) | ||||||
| GG | 522 | 752 | 1.00 | |||
| AG | 236 | 257 | 1.34 | 1.08 | 1.65 | |
| AA | 18 | 26 | 1.04 | 0.56 | 1.93 | 0.03 |
| AG+AA | 1.31 | 1.07 | 1.61 | |||
| rs7796139 (IVS1-34103A>G) | ||||||
| AA | 370 | 543 | 1.00 | |||
| AG | 337 | 423 | 1.17 | 0.96 | 1.42 | |
| GG | 70 | 68 | 1.52 | 1.06 | 2.18 | 0.02 |
| AG+GG | 1.21 | 1.00 | 1.46 | |||
| rs759158 (IVS1-30770G>T) | ||||||
| TT | 253 | 351 | 1.00 | |||
| GT | 372 | 502 | 1.03 | 0.83 | 1.27 | |
| GG | 151 | 181 | 1.16 | 0.88 | 1.52 | 0.33 |
| GT+GG | 1.06 | 0.87 | 1.30 | |||
| rs7796872 (IVS1-30135G>A) | ||||||
| GG | 593 | 780 | 1.00 | |||
| AG | 170 | 236 | 0.94 | 0.75 | 1.18 | |
| AA | 11 | 18 | 0.76 | 0.36 | 1.63 | 0.43 |
| AG+AA | 0.94 | 0.75 | 1.17 | |||
| IGFBP3 | ||||||
| rs6670 (Ex5-411A>T) | ||||||
| TT | 514 | 740 | 1.00 | |||
| AT | 227 | 261 | 1.24 | 1.00 | 1.53 | |
| AA | 30 | 31 | 1.40 | 0.84 | 2.36 | 0.03 |
| AT+AA | 1.27 | 1.04 | 1.56 | |||
| rs13223993 (Ex5+615C>T ) | ||||||
| GG | 506 | 702 | 1.00 | |||
| AG | 247 | 294 | 1.15 | 0.94 | 1.42 | |
| AA | 24 | 37 | 0.87 | 0.51 | 1.49 | 0.46 |
| AG+AA | 1.11 | 0.91 | 1.36 | |||
| rs2270628 (4848 bp 3′ of STPG>A) | ||||||
| CC | 514 | 676 | 1.00 | |||
| CT | 230 | 319 | 0.94 | 0.77 | 1.16 | |
| TT | 27 | 34 | 1.04 | 0.62 | 1.76 | 0.73 |
| CT+TT | 0.95 | 0.78 | 1.16 | |||
1
Adjusted for age, sex, and center.