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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Eur J Pain. 2008 Jun 24;13(4):380–386. doi: 10.1016/j.ejpain.2008.05.008

Fig. 2.

Fig. 2

QHEND reduces tactile allodynia measured by differential weight-bearing in naïve rats. Inoculation of QHEND (open circles) but not QOZHG (filled squares) subcutaneously 3 days prior to CFA significantly increased the ability of the animals to bear weight on the CFA-injected paw (a); P < 0.01, general linear model, repeated measures test (SPSS); n = 6 animals per group. This effect was reversed by intrathecal (b) or intraperitoneal (c) Nal-M tested 3 days after CFA; behavioral testing was carried out 30 min after administration of Nal- M; *P < 0.05 pre Nal-M (filled bars) vs post Nal-M (open bars), t-test; n = 6 animals per group.