Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Mar 25;4(3):e4968. doi: 10.1371/journal.pone.0004968

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Lam et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A, Quantitative RT-PCR analysis of the expression levels of gene markers associated with different subtypes of breast tumors. The RNA was extracted from cultured primary tumor cells isolated from 14-week old PyVT(+/−)/ADN(+/+) and PyVT(+/−)/ADN(+/−) female FVB/N mice and quantitative PCR analysis performed as described in the Methods. *, P<0.01 vs PyVT(+/−)/ADN(+/+) group, n = 10. B, Morphological features of tumors derived from 14-week old female PyVT(+/−)/ADN(+/+) and PyVT(+/−)/ADN(+/−) mice of the FVB/N background. Distinct morphologies were observed between tumors collected from mice with normal and reduced adiponectin levels. Note that central necrosis and geographic tumor necrosis, as well as stromal lymphocytic responses represented the typical basal-like subtype of breast tumors in PyVT(+/−)/ADN(+/−) mice. C, The protein levels of p53 were much higher in tumors derived from PyVT(+/−)/ADN(+/+) mice compared to those of the PyVT(+/−)/ADN(+/−) mice as measured by Western Blotting using specific antibodies purchased from Cell Signaling Biotechnology.