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TABLE 3.

Correlations between changes in plasma lipids and lipoproteins and plasma sterols per statin treatment

Rosuvastatin (n = 66)
Atorvastatin (N = 69)
Δ TC Δ LDL-C Δ HDL-C Δ TG Δ sdLDL-C Δ TC Δ LDL-C Δ HDL-C Δ TG Δ sdLDL-C
Δ Lathosterol 0.406b 0.346d 0.200 0.049 0.337d 0.390b 0.331d 0.042 0.216 0.274c
Δ Campesterol 0.233 0.231 0.022 −0.026 −0.082 0.311d 0.298c 0.071 0.164 0.188
Δ Sitosterol 0.229 0.214 0.170 0.012 −0.104 0.252c 0.186 0.149 0.162 0.268c
Δ Cholestanol 0.240 0.258c 0.047 −0.140 −0.087 −0.168 −0.128 0.080 −0.112 0.008
Δ Lathosterol/Ca 0.301c 0.238 0.127 0.0.69 0.285c 0.144 0.139 0.044 −0.011 0.126
Δ Campesterol/Ca −0.124 −0.104 −0.239 0.106 −0.118 0.055 −0.028 −0.012 0.170 0.168
Δ Sitosterol/Ca −0.216 −0.242 −0.065 0.205 −0.195 −0.013 −0.119 0.057 0.134 0.201
Δ Cholestanol/Ca −0.165 −0.135 −0.193 −0.001 −0.052 −0.376d −0.317d 0.078 −0.135 −0.076
Δ Lathosterol/campesterol ratio 0.231 0.211 0.072 0.055 0.264c 0.084 −0.001 −0.021 0.191 0.230
a

Ratio of the plasma sterols to 102 umol/mmol of cholesterol. TC, total cholesterol; TG, triglycerides.

b

P < 0.001.

c

P < 0.05.

d

P < 0.01.