Skip to main content

TABLE 5.

Subgroup combinations of lathosterol and campesterol changes in relation to changes in total cholesterol and LDL cholesterol during statin treatment

Lathosterol decrease Campesterol change N Changes in total cholesterol, mg/dl Changes in LDL-C, mg/dl
High Increase 32 −107 (38)a −99 (33)c
High Decrease 37 −132 (30)a,b −124 (32)c,d
Low Increase 30 −97 (40)b −94 (38)c
Low Decrease 36 −112 (32) −107 (31)

Values are means (SD). A high decrease in lathosterol is defined as a decrease greater than 6.3 μmol/L. The symbols indicate significant pairs derived from post hoc testing. Tests for significance were adjusted using the Bonferroni method for multiple comparisons.

a

P = 0.027.

b

P = 0.001.

c

P = 0.015.

d

P = 0.003.