Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutation of Per2 leads to vascular senescence. A, Cumulative population doubling is decreased in murine lung endothelial cells (EC) isolated from 8-week-old Per2m/m mice (n=4). B, One-year-old Per2m/m mice have increased percentage of senescence-related β-galactosidase staining positive compared with mice (n=4). C, Representative images of en face aorta or endothelial cells with senescence-related β-galactosidase staining (n=6). *P<0.05 vs WT.
