Tables 5.
T-values, MNI coordinates and corresponding Brodman areas (BA) of highest activated voxels within two pre-defined brain ROIs, the extended etxrastriate cortex and amygdala, respectively. Upper panel: ROI sub-regions showing stronger activation during reading of emotional (pleasant and unpleasant) versus neutral adjectives. Middle panel: ROI sub-regions showing stronger activation during reading of pleasant versus neutral adjectives. Bottom panel: ROI sub-regions showing stronger activation during reading of pleasant versus unpleasant adjectives.
Hemisphere | Brain regions of interest | Brodman area (BA) | T–value | Coordinates x, y, z MNI | Cluster |
---|---|---|---|---|---|
Emotional adjectives > neutral adjectives | |||||
Extrastriate ROI | |||||
Left | Occipital lobe | ||||
Extrastriate cortex | BA 18/19 | 6.15 | −18 −98 −2 | 198** | |
Inferior temporal lobe | |||||
Left | Inferior temporal gyrus | BA 20 | 3.20 | −38 −10 −28 | 3 |
Fusiform gyrus | BA 20 | 3.13 | −38 −12 −26 | 8 | |
Amygdalar ROI | |||||
Left | Amygdala | 4.14 | −20 −2 −24 | 25** | |
Pleasant adjectives > neutral adjectives | |||||
Extrastriate ROI | |||||
Occipital lobe | BA18/19 | 5.25 | −20 −98 −4 | 311** | |
Left | Extrastriate cortex | ||||
Inferior temporal lobe | |||||
Left | Inferior temporal gyrus | BA 20 | 4.19 | −36 −8 −26 | 18 |
Fusiform gyrus | BA 19 | 3.77 | −42 −68 −16 | 43* | |
Amygdalar ROI | |||||
Left | Amygdala | 4.77 | −20 −2 −24 | 20** | |
Pleasant adjectives > unpleasant adjectives | |||||
Extrastriate ROI Occipital lobe | |||||
Left | Extrastriate cortex | BA 19 | 4.37 | −46 −74 −6 | 73** |
Amygdalar ROI | |||||
Left | Amygdala | 3.25 | −18 2 −22 | 6* |
aROI-effects characterized by a significant increase (after small volume correction ∼ SVC) during reading emotional adjectives compared to reading neutral adjectives. bComparison of reading pleasant with reading neutral adjectives. cComparision of reading pleasant with reading unpleasant adjectives. Asterixes (** and *) indicate that effects are significant at cluster level corresponding to **P < 0.005 and *P < 0.05 corrected for multiple comparison within small volumes (SVC) in each of the two ROIs. Because the extra-striate ROI comprised several different anatomical structures, the locations of clusters of significant activity within this ROI are further detailed in the tables. SVC was applied across all voxels of the ROIs, separately for the amygdala and the extra-striate ROI. ROI analysis did not reveal any supra-threshold activity for the contrasts unpleasant > neutral, unpleasant > pleasant, neutral > pleasant or neutral > unpleasant.