Figure 2.
Timeline for the pilot study, designed to test the utility of the IUCS in supporting normal human fertilization and embryo development. For each patient, after ICSI, half of the injected oocytes were allocated to the IUCS arm (in vivo) and the other half to the in vitro arm. The times were selected to assess the IUCS for the following aspects of early development—Group 1: Day 0 to 1, in vivo fertilization; Group 2: Day 1 to 3, in vivo early embryo development and Group 3: Day 0 to 3, in vivo fertilization and early embryo development.
