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. Author manuscript; available in PMC: 2009 Mar 17.
Published in final edited form as: J Biol Chem. 2005 Nov 18;281(7):4173–4182. doi: 10.1074/jbc.M510628200

FIGURE 5. The processing of HIV-1 and ASV U5 duplex oligo substrates by HIV-1/RSV chimeras with amino acid exchanges at drug-resistant sites.

FIGURE 5

The processing of U5 duplex oligo substrates by IN was as described in the legend to Fig. 3. A, HIV-1 U5 LTR duplex oligo. B, ASV U5 LTR duplex oligo. HIV-1 IN (3CSF185H), lane 1; ASV IN, lane 5; no enzyme (−), lane 6. HIV-1/ASV chimeras (see Table 1 for specific amino acid substitutions): S72, lane 2; S125; lane 3; S153, lane 4. Notations used are as in Fig. 3.