(a) Section through a tomogram of myosin V in the inhibited state, adsorbed on a lipid monolayer, showing the para-crystalline, hexagonal arrangement of the “flower motifs” with one of the flower motifs highlighted. Inset: a petal of the flower motif with the molecular domains of myosin V highlighted. Red: motor domains, yellow: cargo-binding domain, blue: S2 domain, green: lever arms. (b) Histogram of the tilt axis directions (0° to 180°) in all aligned subvolumes with respect to the myosin V structure (“petals” within a flower motif). Note that not all orientations are equally represented, due to the para-crystalline arrangement.