Table 1.

Summary of domains unfolding degree of the mutated systems after a simulation was performed.

		Secondary structure details
Mutated system	Sequence	Native	Mutant	Unfolding degree	Affected domain
B10Leu	47–48	HH	RR	–	CD
B10Tyr	48	H	T	–	CD
	52–57	HHHHHH	TTTTRR	Total	HD
B10Val	43–48	HHHHHH	RTTTTT	–	CD
	52–58	HHHHHHH	TTTRTTT	Total	HD
	97–100	HHHH	TTTT	Parcial	HF/FG
E7His	47–48	HH	RR	–	CD
E7Asn	47–48	HH	RR	–	CD
E7Val	42–48	HHHHHHH	RRRRRRT	Parcial	HC/CD
	56–58	HHH	RRR	Parcial	HD
E11Val	36–48	HHHHHHHHHHHHH	TTTTTTTTTTTTR	Total	HC/CD
	52–57	HHHHHH	TTTRRR	Total	HD
B10LeuE7His	47	H	T	–	CD
	52–57	HHHHHH	TTTTTR	Total	HD
B10LeuE11Val	39–48	HHHHHHHHHH	TTTTTTTTTT	Parcial	HC/CD
	52–58	HHHHHHH	TTTTTTT	Total	HD

The sequence (column2) secondary structure is represented by H, Rand T (columns 3 and 4), which represents the α-helical, random coil, and β-turn domains, respectively. The CD domain represents the loop that connects the C and D helices.