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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Microbes Infect. 2008 Apr 22;10(7):773–780. doi: 10.1016/j.micinf.2008.04.008

Table 1.

Aerosolized ΔmglA does not protect against respiratory U112 infection

Mouse strain ΔmglA deposition dose (CFU/lung) U112 challenge deposition dose (CFU/lung)a Survival at 96 hoursd
C57BL/6 2 × 103
2 × 103 		8 × 104
2 × 103 		0/4
0/4
BALB/c 1 × 105
3 @ 1 × 105b 		6 × 102
35c 		0/4
0/4
a

Except where noted, U112 challenges were performed 6-8 weeks after ΔmglA infections.

b

Intervals between three successive ΔmglA infections were 8 and 4 weeks.

c

U112 challenge was performed 4 weeks after third ΔmglA infection.

d

Mice were observed for death or illness, and euthanized when moribund. Unvaccinated C57BL/6 mice challenged with 8 × 104 CFU/lung U112 and BALB/c mice challenged with 6 × 102 CFU/lung U112 had 100% mortality at 96 hours (n=4 per group).