Table 2.
Virus (Region sequenced) | Dinucleotide context of G-to-A Mutations | ||||
GGa (%) | GA (%) | GC (%) | GT (%) | Total | |
WT (Vif/Vpr) | |||||
DNA | 1 (25%) | 3 (75%) | 0 | 0 | 4 |
Cellular viral RNA | 0 | 0 | 0 | 0 | 0 |
Virion RNA | 7 (32%) | 11 (50%) | 1 (5%) | 3 (14%) | 22 |
HIV-YRHHY>A5 (Vif/Vpr) | |||||
DNA | 620 (87%) | 83 (12%) | 6 (1%) | 3 (0.4%) | 712 |
Cellular viral RNA | 81 (86%) | 9 (10%) | 3 (3.2%) | 1 (1%) | 94 |
Virion RNA | 34 (69%) | 10 (20%) | 3 (6%) | 2 (4%) | 49 |
HIV-YRHHY>A5 (DIS/Gag) | |||||
DNA | 54 (87%) | 8 (13%) | 0 | 0 | 62 |
Cellular viral RNA | 74 (89%) | 3 (4%) | 3 (4%) | 3 (4%) | 83 |
Virion RNA | 20 (74%) | 4 (15%) | 0 | 3 (11%) | 27 |
a The first G nucleotide in the GG dinucleotide is the target of G-to-A mutation.